Systemic non-albicans infections presented as meningitis in chronic hepatitis B patient: a case report

发表时间：2015-11-18 浏览次数：2051次

引用：

Lv WJ, Bu H, He JY, Sun RR, Zou YL. Systemic non-albicans infections presented a

关键词：

作者：

Wen-Jing Lv, Hui Bu, Jun-Ying He, Ran-Ran Sun, Yue

作者单位：

Department of Neurology, Second Hospital of Hebei

出版年份：

2014

期刊页数：

161-164

收录者：

其他外文数据库

摘要：

Non-albicans candida meningitis is a relatively rare disease, with nonspecific clinical manifestation, which makes the misdiagnosis occur sometimes, especially in the early stage of the disease. Abuse of broad-spectrum antibiotics, corticosteroids, central vein cannulas, senility, big operation, malignancy, and total parenteral alimentation were all the susceptible factors of non-albicans candida infection. We present a case of this type of non-albicans infection in a 42-year-old woman who was early misdiagnosed as tuberculous meningitis and was treated with antibiotics and antituberculosis agents. The diagnosis of non-albicans infection was confirmed by fungus culture of the cerebrospinal fluid (CSF) with a low detectable rate. This case reminds us that the non-albicans candida meningitis had a nonspecific clinical presentations and laboratory data, and was difficult to differentiate from tuberculosis meningitis. Hence, we should highly suspect this disease if central nervous system infections with uncertain pathogens. Test cell counts; protein and fungus culture of CSF should be used to confirm the diagnosis. Once the diagnosis was established, the patients should receive antifungal treatment based on drug sensitivity tests as early as possible.

阅读全文