Toluene-induced leukoencephalopathy with characteristic magnetic resonance imaging findings

发表时间：2015-11-15 浏览次数：1364次

引用：

Zeng F, Yang H, Zhou HD, Wang YJ. Toluene-induced leukoencephalopathy with chara

关键词：

作者：

Fan Zeng, Heng Yang, Hua-Dong Zhou, Yan-Jiang Wang

作者单位：

Department of Neurology and Center for Clinical Ne

出版年份：

2014

期刊页数：

92-94

收录者：

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摘要：

Toluene-induced leukoencephalopathy is a frequently seen medical condition worldwide; however the lack of specific clinical manifestations and laboratory tests makes it difficult to diagnose. Neuroimaging and medical history are often crucial to diagnosis of this disorder. In this report, a case is presented of a patient suffering from toluene-induced leukoencephalopathy with deteriorating cognition impairment and characteristic magnetic resonance imaging (MRI) findings, typified by a "sunflower-like" change in T2-weighted imaging. In addition, the pharmacokinetic properties of toluene are reviewed, as well as the clinical manifestations, typical MRI findings, neuropathology, possible mechanism, and treatment of toluene-induced leukoencephalopathy.

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