Effect of conduction block in classification and prognosis of Guillain-Barre syndrome

发表时间：2015-11-15 浏览次数：1503次

引用：

Wang YC, Feng GD, Wang J, Liu XD, Zhao G. Effect of conduction block in classifi

关键词：

作者：

Yu-Chen Wang, Guo-Dong Feng, Jing Wang, Xue-Dong L

作者单位：

Department of Neurology, Xijing Hospital, The Four

出版年份：

2014

期刊页数：

77-81

收录者：

其他外文数据库

摘要：

Aim: The aim was to investigate the electro-physiological characteristics in disease progression of Guillain-Barre syndrome (GBS) and observe the effect of conduction block (CB) in classification and severity of the disease. Methods: Two hundred and ninety-four patients with GBS were divided into acute inflammatory demyelinating poly-neuropathy (AIDP) group, acute motor axonal neuropathy (AMAN) group and equivocal group according to their electro-physiological results and then reclassificated after electro-physiological review. All of the patients were followed for 6 months since their attacks. Results: Bad prognosis is more pronounced in AMAN group than in AIDP group (P < 0.05). Most of the patients classificated as AIDP transformed into AMAN when CB occurred in the early phase of the disease. There is a positive relationship between CB in the early phase of the disease and severity of illness (P < 0.05), but CB showed no correlation with prognosis of the patients (P > 0.05). Conclusion: CB in the early phase of GBS indicates the probability of AIDP transforming into AMAN; it suggests that patients with CB in the early phase of the disease might be in serious conditions in a certain extent.

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