Pyroptosis and neurological diseases

发表时间：2015-11-15 浏览次数：1422次

引用：

Xie Z, Zhao G. Pyroptosis and neurological diseases. Neuroimmunol Neuroinflammat

关键词：

作者：

Zhen Xie1, Gang Zhao2

作者单位：

1 Department of Neurology, Xijing Hospital, Forth

出版年份：

2014

期刊页数：

60-65

收录者：

其他外文数据库

摘要：

Pyroptosis is a new process of programmed cell death, which has been discovered and confirmed in recent years. Its cardinal features include activation of caspase-1 and a massive release of inflammatory cytokines (interleukin (IL)-1β, IL-18), etc. The morphological characteristics, occurrence and regulatory mechanisms of the pyroptosis greatly, differ from other cell death mechanisms such as apoptosis and necrosis. It has already been proven that pyroptosis participates and plays an important role in a wide range of neuronal diseases. Here, we review the current understanding of the pyroptosis and its roles in neurological diseases.

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