Anti-N-methyl-D-aspartate receptor encephalitis in China

发表时间：2015-11-15 浏览次数：1311次

引用：

Li L, Wang CB, Zhao G. Anti-N-methyl-D-aspartate receptor encephalitis in China.

关键词：

作者：

Li Li1, Cheng-Bin Wang2, Gang Zhao1

作者单位：

1 Department of Neurology, Xijing Hospital, Fourth

出版年份：

期刊页数：

17-23

收录者：

其他外文数据库

摘要：

N-methyl-D-aspartate receptors (NMDARs) are mainly distributed in the central nervous system, and play important roles in the mechanisms of learning and memory. A newly discovered disease caused by autoantibody to NMDAR has been described, and is called anti-NMDAR encephalitis. Patients with this disease often suffer from mental disorders, seizures and other encephalitis-like symptoms. Accumulated data suggests that the severity of the disease makes early diagnosis very important. Accurately detecting the autoantibody to NMDAR is considered to be the gist of diagnosis. Good prognosis is predicted in most patients, when treated properly. Immunotherapy is preferred in most cases. In China, this disease has been reported only for a few years, but sporadic case reports are also helpful for profiling

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