曲安奈德后筋膜下注射联合532激光光凝治疗糖尿病弥漫性 黄斑水肿的疗效观察
发表时间:2014-04-23 浏览次数:829次
黄晓燕,刘贤金,黄玉银,曾振培.曲安奈德后筋膜下注射联合532激光光凝治疗糖尿病弥漫性 黄斑水肿的疗效观察[J].吉林医学,2014,35(12):2341-
糖尿病;黄斑水肿;曲安奈德;激光;后筋膜下
黄晓燕,刘贤金,黄玉银,曾振培
广东省湛江市第二人民医院眼科,广东 湛江 52400
2014
2341-2343
知网
目的:探讨曲安奈德后筋膜下注射联合倍频532激光光凝治疗糖尿病弥漫性黄斑水肿的治疗效果及安全性。方 法:将确诊弥漫性糖尿病黄斑水肿患者46例(46眼)分先行曲安奈德20mg后筋膜下注射,1周后再行格栅样“C”形光凝联合全 视网膜光凝,对比治疗前后最佳矫正视力、眼压、眼底荧光血管造影及OCT情况。结果:注药前平均视力018±012,激光后 2周、3个月、6个月平均视力分别提高至(035±012)、(045±016)、(036±020),黄斑中心凹的厚度,治疗前(39336± 9218)μm,治疗后2周、3个月、6个月分别是(25341±6673)μm、(24940±5864)μm、(25041±6073)μm,两组治疗后和治 疗前比较均有统计学意义(P<005),治疗后发生眼压增高3眼(65%)经治疗后好转,无晶状体混浊加重,结论:曲安奈德后筋 膜下注射联合532激光光凝治疗糖尿病弥漫性黄斑水肿有效,且无明显并发症,适合基层医院进一步推广。 Observationoftheeffectsofdiffuseddiabeticmacularedemabyposteriorfasciainjectionoftriamcinolonecombinedwith532laserphotocoagulation HUANGXiao-yan,LIUXian-jin,HUANGYu-yin,etal(OphthalmologyofZhanjiangsecondpeople'sHospital,ZhanjiangGuangdong524000,China)Abstract:ObjectiveTodiscusstheeffectsandthesafetyofposteriorfasciainjectionofTriamcinolonecombinedwith532laserphotocoagulationtreatedondiffuseddiabeticmacularedemaMethods46casesofdiffuseddiabeticmacularedema(46eyes)inourhospital吉林医学2014年4月第35卷第11期 ·2341· weretreatedbyposteriorfasciainjectionof20mgTriamcinolonefirst.After1week,allthepatientsweretreatedbygridpatternphotocoagulationatmacularregionandpanretinalphotocoagulation.Thebestcorrectedvisualacuity,IOP,fluorescencefundusangiographyandOCTwerecompared.ResultsThevisualacuitybeforetreatmentwas018±0122weeks,3monthsand6monthsaftertreatment,thevisualacuitywas035±012,045±016,036±020respectively.Thecentralfovealthicknesswas39336±9218μm beforetreatment.2weeks,3monthsand6monthsaftertreatment,thecentralfovealthicknesswas25341±6673μm,24940±5864μm,25041± 6073μmrespectively.Thedifferencebetweenbeforeandaftertreatmentwasstatisticallysignificant(P