Natural products and hepatocellular carcinoma: a review
发表时间:2015-11-12 浏览次数:1278次
Alnajjar AM, Elsiesy HA. Natural products and hepatocellular carcinoma: a review
Asma M Alnajjar1, Hussien A Elsiesy2
1 College of Medicine, Alfaisal University, Riyadh
2015
119-124
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Hepatocellular carcinoma (HCC) is the fifth commonest cause of malignancy and the third cause of cancer mortality. There are different treatment options for HCC ranging from loco-regional therapy to surgical treatment. Different regimen of systemic chemotherapy has been tried with a poor response. Several studies aimed at discovering more molecules for the management of HCC. Those studies aimed at recognizing and targeting several signaling and molecular pathways that lead to cellular proliferation and tumor formation. In this review, we discussed the role of several agents found in natural and dietary products such as curcumin, resveratrol, flavonoids, Rubus aleaefolius Poir total alkaloids, Livistona chinensis seed, and crocetin. We had used the names of the above-mentioned products as key words in addition to "HCC" on PubMed to find studies that discussed their roles in HCC. Articles were downloaded for reviewing and discussing natural products that had adequate studies in treating HCC.