米索前列醇直肠给药联合应用缩宫素预防剖宫产术后出血60例临床观察

发表时间：2014-01-21 浏览次数：457次

引用：

张洪波.米索前列醇直肠给药联合应用缩宫素预防剖宫产术后出血60例临床观察[J].吉林医学,2014,35(1):44-45.

关键词：

米索前列醇；缩宫素；产后出血；直肠给药

作者：

张洪波

作者单位：

北京市顺义区中医医院，北京101300

出版年份：

2014

期刊页数：

44-45.

收录者：

知网,万方

摘要：

目的：观察米索前列醇600 μg直肠放置联合应用缩宫素预防剖宫产术后出血的临床疗效。方法：选择2011年3月~2012年9月在产科住院采用腰硬联合麻醉方式行剖宫产术分娩产妇120例，随机分为实验组和对照组各60例，方案为剖宫产术中胎儿娩出后，实验组即刻宫体注射缩宫素20 U，将米索前列醇600 μg放入直肠，深度5～6 cm。对照组宫体注射缩宫素20 U，同时静脉滴注缩宫素20 U。观察两组产后2 h、产后24 h出血量及产后出血的例数。结果：两组产后2 h、24 h出血量及产后出血发生率比较，差异有统计学意义（P﹤0.05）。结论：米索前列醇直肠给药联合应用缩宫素预防剖宫产术后出血优于单纯应用缩宫素，价格低，使用简便，值得在基层医院推广应用。 ObjectiveTo observe the clinical effect of combined use of rectal placed misoprostol 600 ug and oxytocin to prevent bleeding after cesarean section.MethodWe chosed 120 patients in obstetrical department of our hospital from Mar.2011 to Sep.2012.They all underwent cesarean section with the waist hard way combined anesthesia to delivery，and were randomly divided into the experimental group and the control group.After the fetal childbirth，the experiment group would inject oxytocin 200 and misoprostol 600 ug into the rectum about 5 ~ 6cm depth.Control group inject oxytocin 200 and intravenous drip oxytocin 200 in the same time.We recorded the two groups′ amount of bleeding of postpartum for 2 hours and postpartum 24 hours，and the number of postpartum hemorrhage.ResultsThe amount of bleeding and postpartum hemorrhage rate comparison in two groups of postpartum 2 hours and 24 hours was significantly different (P﹤0.05).ConclusionMisoprostol rectally use combined with application oxytocin can prevent bleeding after cesarean section，and is better than the simple application of oxytocin.It is worth to use in primary hospitals for its low price and accessibility.

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