HPLC法测定洛索洛芬钠缓释微丸中洛索洛芬钠的含量
发表时间:2014-06-03 浏览次数:1114次
商萍,李婷.法测定洛索洛芬钠缓释微丸中洛索洛芬钠的含量[J].黑龙江医药,2012,25(2).196-197
洛索洛芬钠;缓释微丸;高效液相色谱法
商萍,李婷
哈药集团三精制药股份有限公司
2012
196-197
知网
目的:本文通过对洛索洛芬钠微丸的含量测定研究,建立一种高效的含量测定方法,为制备洛索洛芬钠微丸型制剂的安全有效和稳定行提供科学依据。进而为剂型选择,处方设计,工艺及质量控制提供理论基础。方法:采用高效液相色谱法对洛索洛芬钠的含量进行测定。结果:通过方法学考察发现,洛索洛芬钠缓释微丸中洛索洛芬钠的含量稳定性良好,方法适宜。 Objective:We study by measuring the Loxoprofen sodium in the content of Loxo sustained release pellets.We establish an efficient method.Preparation of Loxo sustained release pellets was provided a scientific basis on safe effective and stable lines.And then it provides a theoretical basis for Selecting the prescription formulations designing to process and quality controlled.Methods:We measure the content of Loxo sustained release pellets by HPLC.Results:By study the methodology we found that the content is stable and also the method is appropriate.