持续性皮下胰岛素输注对初诊2型糖尿病患者胰岛β细胞功能及脂联素、内脂素的影响

发表时间：2014-01-21 浏览次数：702次

引用：

胡郁刚1，陈根本2.持续性皮下胰岛素输注对初诊2型糖尿病患者胰岛β细胞功能及脂联素、内脂素的影响[J].吉林医学,2014,35(3):458-460.

关键词：

作者：

胡郁刚1，陈根本2

作者单位：

1.广东省潮州市潮州医院内二科，广东潮州 521000；2.广东省潮州市潮安县庵埠华侨医院内二

出版年份：

2014

期刊页数：

458-460

收录者：

万方

摘要：

目的：观察短期持续性皮下胰岛素输注（Continuous Subcutaneous Insulin Infusion，CSII）对初诊2型糖尿病患者胰岛β细胞功能及脂联素、内脂素的影响。方法：将62例初诊2型糖尿病患者随机分为治疗组与对照组，治疗组采用CSII，对照组仅皮下注射胰岛素，疗程共2周，比较两组治疗前后胰岛β细胞功能指标的变化，治疗前后均检测脂联素、内脂素，计算HOMA-IR（C-P），比较两组治疗前后胰岛素抵抗的变化。结果：治疗后，治疗组胰岛β细胞分泌功能、脂联素均显著升高，内脂素和胰岛素抵抗指数显著降低。差异有统计学意义（P＜0.05）。结论：持续性皮下胰岛素输注对初诊2型糖尿病患者有积极作用。 Objective To observe the short-term continuous subcutaneous insulin infusion in patients with newly diagnosed type 2 diabetes,β-cell function and adiponectin、visfatin effects.Methods 62 patients were randomly divided into treatment and control groups,treatment group with CSII,the control group,only subcutaneous insulin injections daily for 2 weeks,two groups were compared before and after treatment of β-cell function index changes.Before and after treatment are within a detecting adiponectin,visfatin,calculated HOMA-IR(C-P).Results After treatment,the treatment group islet β-cell secretion,adiponectin were significantly elevated,visfatin and insulin resistance index decreased significantly.The difference was statistically significant(P＜0.05).Conclusion Continuous subcutaneous insulin infusion for first diagnosis in patients with type 2 diabetes have a positive effect

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持续性皮下胰岛素输注对初诊2型糖尿病患者胰岛β细胞功能及脂联素、 内脂素的影响

持续性皮下胰岛素输注对初诊2型糖尿病患者胰岛β细胞功能及脂联素、内脂素的影响