缬沙坦分散片与雷公藤多甙在治疗78例糖尿病肾病蛋白尿中的效果分析

发表时间：2014-01-20 浏览次数：688次

引用：

蒲艳,邹庆伟,蒲敏等.缬沙坦分散片与雷公藤多甙在治疗78例糖尿病肾病蛋白尿中的效果分析[J].吉林医学,2013,34(28):5789-5791.

关键词：

缬沙坦分散片知识脉络雷公藤多甙知识脉络糖尿病知识脉络肾病蛋白尿知识脉络

作者：

蒲艳[1] 邹庆伟[2] 蒲敏[3]

作者单位：

泸州医学院附属中医医院内科,四川,泸州,646000 泸州医学院附属医院胃肠外科,四川,泸州

出版年份：

2013

期刊页数：

5789-5791

收录者：

知网,万方

摘要：

目的:探讨缬沙坦分散片联合雷公藤多甙治疗糖尿病患者肾病蛋白尿的疗效.方法:将糖尿病伴肾病蛋白尿的患者随机分成两组,对照组和观察组各98例.对照组服用缬沙坦分散片,观察组加载服用雷公藤多甙.比较两组患者的疗效差异,检测疗前及疗后24 h尿蛋白、尿白蛋白排泄率、尿β2微球蛋白含量.结果:治疗4周后,观察组疗效显著优于对照组差异有统计学意义(P＜0.05);治疗4周后,两组患者的24 h尿蛋白、尿白蛋白排泄率、尿β2微球蛋白与疗前相比,均有不同程度的改善,差异具统计学意义(P＜0.05);观察组各个指标的改善情况显著优于对照组,P＜0.05.结论:缬沙坦联合雷公藤多苷能有效治疗糖尿病肾病,改善蛋白尿症状. ObjectiveTo investigate the efficacy of valsartan dispersible tablets and tripterygium of glycosides in the treatment of patients with diabetic nephropathy proteinuria.MethodPatients treated in our hospital of diabetes with nephrotic proteinuria were randomly divided into two groups，the control group and the observation group，and 98 cases in each group.The control group was taken with valsartan dispersible tablets，and the observation group was taken with Tripterygium glycosides.The differences of the efficacy for the two groups were compared.The 24h urine protein were detected before treatment and after treatment，urinary albumin excretion rate，urinary β2 microglobulin content of the two groups were detected.ResultsAfter 4 weeks of treatment，the efficacy in the observation group was significantly better than the control group (P

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