血清胱抑素C 联合尿β2微球蛋白测定对早期肾损伤评价的临床意义

发表时间：2014-06-06 浏览次数：1074次

引用：

崔惠芬，石波，罗冬改.血清胱抑素C 联合尿β2微球蛋白测定对早期肾损伤评价的临床意义.引用：[J].吉林医学,2014,35(15).3205-3206

关键词：

血清胱抑素C；尿β2微球蛋白；早期肾损伤；

作者：

崔惠芬，石波，罗冬改

作者单位：

广东省东莞市寮步医院内二科，广东东莞 523400

出版年份：

2014

期刊页数：

3205-3206

收录者：

知网,万方

摘要：

目的：分析血清胱抑素C联合尿β2微球蛋白检测在早期肾损伤评价中的临床意义。方法：选择100例患者进行研究，将60 例尿蛋白阴性患者设为A组，将40例尿蛋白阳性患者设为B组，选择60例体检健康者为对照组。对A组、B组及对照组尿液中的β2微球蛋白含量及血液中的血清胱抑素C含量进行检测，比较三组的检测结果。结果：A组、B组血清胱抑素C含量分别为（1.66±0.28）和（4.11±0.87），尿β2微球蛋白含量分别为（0.48±0.19）和（0.82±0.22），高于对照组的（0.83±0.19）和（0.32±0.18）；且B组高于A 组。结论：发生早期肾损伤和患者体内血清胱抑素C含量及尿β2微球蛋白含量密切相关，将两者联合检测能够提高诊断的准确性。 Objective Serum cystatin C and urinary β2 microglobulin in the early detection of renal damage assessment to analyze the clinical significance.Methods 100 cases of patients Study,the 60 cases of urinary protein negative patients in group A was set,the 40 cases of patients with positive urine protein set group B,60 patients with healthy subjects as controls.For A,B groups and the control group urine β2-microglobulinlevels,and blood serum cystatin C levels were detected,the test results were compared three groups.Results By comparison,serum cystatin C levels and urinary β2-microglobulin levels,A,B two higher;A,B two sets of test results compared to group B than in group A.Conclusion Occurred early renal damage and in vivo serum cystatin C levels and urinary β2-microglobulin levels are closely related,the combined detection can improve the accuracy of diagnosis.

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