大量输血对凝血功能影响的临床分析

发表时间：2014-02-10 浏览次数：1109次

引用：

梁　智，方　芳.大量输血对凝血功能影响的临床分析[J].吉林医学，2014,35(4):733-734.

关键词：

大量输血;冰冻血浆;凝血功能

作者：

梁　智，方　芳

作者单位：

广西南宁市第一人民医院，广西　南宁　530022

出版年份：

2014

期刊页数：

733-734.

收录者：

万方

摘要：

目的：探讨大量输血后凝血功能的变化和及时输注血浆和(或)血小板的重要性。方法：选择104例大量输血患者，分成单纯输血组、输注红细胞及输400～1000ml血浆组、输注红细胞及超过1000ml血浆组，对输注的成分血及输血前后PT、INR、APTT、FIB、血小板的结果加以分析。结果：大量输血后，患者PT、INR、APTT延长，FIB、血小板下降，单纯输注红细胞患者改变最明显，其次是输红细胞及少量血浆着，输血同时输注1000ml以上血浆凝血机制改变最小。结论：大量输血可使凝血功能变差及血小板降低，适当输注血浆和(或)血小板可减少改变的程度，避免出血加重。 Objective To observe the change of blood clotting function after the massive blood transfusing and the importance of freshfrozen plasma and/ or the platelet transfusing Method 104 patients with massive blood transfusion were divided into three groups： patientswho transfused red blood cell only， patients who transfused red blood cell and 400 ～1 000 ml fresh frozen plasma， patients who transfusedred blood cell and over 1 000 ml fresh frozen plasma Monitoring the PLT and coagulogram of the patients before and after transfusion Results After multiplicity blood transfusion， prothrombin time ( PT) ， internation normalized ratio ( INR) ， activated partial thromboplastintime( APTT) were extending extremely The FIB and the platelet were obviously descending After multiplicity blood transfusion， thePT、 INR、 APTT of patients who transfused red blood cell only were extremely more than patients who transfused red blood cell and fresh frozen plasma， the PT、 INR、 APTT of patients who transfused red blood cell and 400 -1000ml fresh frozen plasma were extremely more thanpatients who transfused red blood cell and over 1 000 ml fresh frozen plasma Conclusion After multiplicity blood transfusion， blood clottingfunction of patients were bad， we should transfuse fresh frozen plasma and/ or the platelet in time， and solve the problem to prevent the severity complications

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