动脉介入治疗消化道肿瘤后腹膜淋巴结转移的临床价值
发表时间:2014-05-04 浏览次数:702次
孙卫东,冯晓峰,周春柳,等.动脉介入治疗消化道肿瘤后腹膜淋巴结转移的临床价值[J].吉林医学,2014,35(13):2743-2745 消化道肿瘤晚期多有后
消化道肿瘤;后腹膜淋巴结转移;介入化疗
孙卫东,冯晓峰,周春柳,任普海,郑永志
中国人民解放军第113医院消化内科,浙江 宁波 315040
2014
2743-2745
知网,万方
目的:探讨采用动脉介入治疗消化道肿瘤后腹膜淋巴结转移的临床价值。方法:选取因消化道肿瘤后腹膜淋巴结转移而住院治疗的56例患者,采用奥沙利铂和5氟尿嘧啶动脉介入的方法治疗,随访12个月观察其疗效(淋巴结的大小、缓解情况、生存率以及生活质量评价等)及不良反应发生情况。结果:术后1个月后疗效评价:淋巴结大小由术前(22.3±5.1)cm2降为术后(10.1±2.3)cm2;完全缓解6例,部分缓解42例,稳定5例,进展3例,总有效率85.7%;术后6个月、12个月生存率分别为83.9%、73.2%;患者的生活质量评价:术前61.30±4.00,术后67.50±6.00。未发生严重不良反应。结论:动脉介入治疗消化道肿瘤后腹膜淋巴结转移是安全有效的,是后腹膜淋巴结转移可以选择的理想治疗方法。当然,该方法仍需进一步的研究评估。 ObjectiveToevaluatetheclinicalvalueofarteryinterventionaltreatmentforretroperitoneallymphnodemetastasisfromgastrointestinaltumors.Method 56patientswithretroperitoneallymphnodemetastasisfromgastrointestinaltumorswereenrolled.Andtheyweregivenoxaliplatinand5-fluorouraciltranscatheterarterialinfusionchemotherapy.Theevaluateefficacysuchasthesizeanddefuseoflymphnodes,thesurvivalrate,qualityoflifescoreandadverseeventswereobservedinayear.ResultsAfteronemonththesizeoflymphnodesbecomefrom(22.3±5.1)cm2to(10.1±2.3)cm2.Andtherewere6casesofcompleteremission,partialremissionin42ca.ses,and5casesofsteadyprogress3cases,andthetotalefficiencywas85.7%.Thesurvivalrateswere83.9% in6months,and73.2% inayear.Thequalityoflifeassessmentbecomefrom(61.30±4.00)to(67.50±6.00).Moreover,therewerenoseriousadversereac.tions.ConclusionArteryinterventionaltreatmentforretroperitoneallymphnodemetastasisfromgastrointestinaltumorsissafeandeffec.tive.Andit′sanidealmethodtocontrolthepainoftheretroperitoneallymphnodemetastases.Ofcourse,thismethodrequiresfurtherstudyassessed.