口腔扁平苔藓患者外周血相关炎症因子表达分析
发表时间:2014-07-11 浏览次数:963次
姜梦雨,姚辉, 杜芳等.口腔扁平苔藓患者外周血相关炎症因子表达分析[J].临床口腔医学杂志.2013,29(4):204-206
口腔扁平苔藓; 红细胞沉降率; C反应蛋白; 类风湿因子;
姜梦雨,姚辉, 杜芳,潘莉俊,唐国瑶
上海交通大学医学院附属第九人民医院口腔医学院口腔黏膜科·上海市口腔医学研究所·上海市口腔医学重点实验
2013
204-206
知网
目的:观察口腔扁平苔藓(OLP)患者外周血中的炎症因子红细胞沉降率、C反应蛋白和类风湿因子的表达。方法:检测20例OLP患者(白纹组与充血糜烂组各10例)和20例类风湿性关节炎(RA)患者外周血的炎症因子血沉、C反应蛋白和类风湿因子指标。结果:OLP患者和RA患者外周血的炎症因子红细胞沉降率(t检验,12.4±10.1 VS 22.6±16.1,P=0.02)、C反应蛋白(t检验,4.6±5.4 VS 26.9±24.7,P=0.0003)和类风湿因子(t检验,9.2±0.2 VS 340.4±541.7,P=0.009)指标之间均有统计学差异。而相应指标在OLP白纹组(5例男性、5例女性,年龄45.1±14.8岁)与充血糜烂组(3例男性、7例女性,年龄49.5±15.2岁)之间无统计学差异(t检验,红细胞沉降率11.9±9.2VS12.9±11.5,P=0.83;C反应蛋白5.7±7.7 VS 3.6±1.0,P=0.39;类风湿因子9.1±0.06 VS 9.2±0.2,P=0.33)。结论:外周血红细胞沉降率、C反应蛋白和类风湿因子与OLP的炎症程度无相关性。 Objective: To investigate the expression of inflammatory-factors hich including erythrocyte sedimentation rate, C -reactive protein and rheumatoid factor, in the peripheral blood of patients with oral lichen planus. Method: Determine the expression of inflammation factors including ESPi, CRP, and RF in peripheral blood of 40 patients, which included 20 patients with oral lichen planus COLP) CI O reticular cases and 10 congestive erosion cases) and 20 patients with rheumatoid arthritis CI}P and RF in the peripheral blood of patients with OLP has no correlation with the severity of inflammation.